SCHEMBL23835673

SCHEMBL23835673

Cc1ccc(COCc2ccc(CC(C)(C)C)cc2)cc1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.54
KCNH2 Q12809 2/20 0.50
AGXT P21549 2/20 0.48
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
TSHR P16473 2/20 0.39
IDO1 P14902 1/20 0.38
THRA P10827 1/20 0.38
THRB P10828 1/20 0.38
MAOB P27338 4/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
MAOA P21397 1/20 0.37
CYP1A2 P05177 1/20 0.35
CYP2A6 P11509 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
ESR2 Q92731 1/20 0.35
PARP10 Q53GL7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL394340 0.87 ESR1 (0.61) ESR1AGXTTSHRIDO1THRA
SCHEMBL9617939 0.84 AGXT (0.64) KCNH2AGXTCA1CA2CA9
SCHEMBL3161372 0.84 AGXT (0.64) KCNH2AGXTCA1CA2CA9
SCHEMBL586154 0.82 AGXT (0.61) KCNH2AGXTCA1CA2CA9
Lithium SCHEMBL585057 0.82 AGXT (0.61) KCNH2AGXTCA1CA2CA9
Potassium SCHEMBL586332 0.82 AGXT (0.61) KCNH2AGXTCA1CA2CA9
SCHEMBL24590308 0.81 AGXT (0.50) ESR1KCNH2AGXTCA1CA2
SCHEMBL23613252 0.81 ESR1 (0.56) ESR1KCNH2TSHRTHRATHRB
SCHEMBL17147385 0.79 TEAD4 (0.54) ESR1AGXTIDO1THRATHRB
SCHEMBL21028444 0.79 ESR1 (0.59) ESR1CA1CA2TSHRIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11127904-B2 Compound, coating composition comprising same, organic light emitting device using same, and manufacturing method thereof LG CHEM, LTD. 2021-09-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11127904-B2 Compound, coating composition comprising same, organic light emitting device using same, and manufacturing method thereof SEM1, FTO, SETDB1 ESR1 303/4885KCNH2 2453/4885AGXT 2413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.