SCHEMBL23837136

SCHEMBL23837136

Bc1cc(B)c(OCC(C)O)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.39
SCN4A P35499 9/20 0.37
MAPT P10636 2/20 0.36
GLA P06280 1/20 0.36
SCN5A Q14524 3/20 0.33
TSHR P16473 2/20 0.33
SCN1A P35498 2/20 0.33
SCN9A Q15858 2/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
NFKB1 P19838 2/20 0.33
CYP2C9 P11712 1/20 0.33
KCNK3 O14649 1/20 0.33
CACNA1F O60840 1/20 0.33
KCNK2 O95069 1/20 0.33
GBA1 P04062 1/20 0.33
MAOA P21397 1/20 0.33
HTR2A P28223 1/20 0.33
SLC6A4 P31645 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20282523 0.85 ATM (0.44) LMNASCN4AMAPTGLASCN5A
SCHEMBL14301005 0.74 TSHR (0.61) LMNASCN4AMAPTGLATSHR
SCHEMBL13207146 0.73 GLA (0.46) LMNASCN4AMAPTGLASCN5A
SCHEMBL11336983 0.70 SCN4A (0.54) LMNASCN4AMAPTTSHRCYP1A2
SCHEMBL7701144 0.69 SCN4A (0.66) LMNASCN4AMAPTSCN5ATSHR
SCHEMBL7701146 0.69 SCN4A (0.66) LMNASCN4AMAPTSCN5ATSHR
SCHEMBL7701472 0.69 SCN4A (0.66) LMNASCN4AMAPTSCN5ATSHR
SCHEMBL27898774 0.69 SCN4A (0.38) LMNASCN4AMAPTGLASCN5A
SCHEMBL14509238 0.68 SCN5A (0.54) LMNASCN4AMAPTSCN5ATSHR
SCHEMBL13083355 0.68 ACHE (0.37) LMNAMAPTCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3555230-B1 ANTIMONY FREE FLAME-RETARDED EPOXY COMPOSITIONS BROMINE COMPOUNDS LTD (IL) 2021-09-22 EP disclosed