Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.33 |
| ▸ | HRH2 | P25021 | 4/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.31 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.31 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8625962 | 0.77 | HTR2C (0.35) | CA1CA2HTR2C | |
| SCHEMBL29659736 | 0.77 | ADRA2A (0.44) | CA1CA2HTR2CHRH3HRH2 | |
| SCHEMBL598145 | 0.77 | ADRA2A (0.44) | CA1CA2HTR2CHRH3HRH2 | |
| SCHEMBL17192148 | 0.74 | GID4 (0.42) | HTR2CHRH3HRH2 | |
| SCHEMBL22143863 | 0.74 | DRD2 (0.40) | HTR2CHRH3HRH2TAS1R3TAS1R1 | |
| SCHEMBL17192147 | 0.74 | GID4 (0.42) | HTR2CHRH3HRH2 | |
| SCHEMBL12270073 | 0.74 | GID4 (0.42) | HTR2CHRH3HRH2 | |
| SCHEMBL1660087 | 0.74 | ADRA2A (0.50) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL12961288 | 0.72 | POLL (0.40) | ACHE | |
| SCHEMBL12434029 | 0.71 | HRH3 (0.35) | CA1CA2HTR2CHRH3HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3137478-B1 | PHOSPHOROUS PROTECTING GROUPS AND METHODS OF PREPARATION AND USE THEREOF | AGILENT TECHNOLOGIES INC (US) | 2021-09-22 | — | — | EP | disclosed |