Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234085 | 0.85 | ALDH1A1 (0.41) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL237531 | 0.84 | ELANE (0.39) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL15404813 | 0.82 | TDP1 (0.46) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL237430 | 0.82 | TSHR (0.40) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL840793 | 0.81 | MAPT (0.46) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL9337758 | 0.81 | ELANE (0.41) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL237893 | 0.78 | THRB (0.46) | ALDH1A1MAPTTSHRKMT2ATHRB | |
| SCHEMBL236261 | 0.76 | ALDH1A1 (0.41) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL27863616 | 0.76 | POLB (0.42) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL10939355 | 0.76 | ELANE (0.37) | ELANEPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |