Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237430 | 0.89 | TSHR (0.40) | ALDH1A1MAPTTHRBELANEKMT2A | |
| SCHEMBL236261 | 0.85 | ALDH1A1 (0.41) | ALDH1A1MAPTTHRBELANEKMT2A | |
| SCHEMBL238397 | 0.85 | ELANE (0.39) | ALDH1A1MAPTTHRBELANEKMT2A | |
| SCHEMBL28054471 | 0.83 | TSHR (0.44) | ALDH1A1MAPTTHRBELANEKMT2A | |
| SCHEMBL238593 | 0.79 | THRB (0.44) | ALDH1A1MAPTTHRBKMT2AMEN1 | |
| SCHEMBL840793 | 0.78 | MAPT (0.46) | ALDH1A1MAPTTHRBELANEKMT2A | |
| SCHEMBL9337758 | 0.78 | ELANE (0.41) | ALDH1A1MAPTTHRBELANEKMT2A | |
| SCHEMBL27863692 | 0.77 | THRB (0.44) | ALDH1A1MAPTTHRBELANEKMT2A | |
| SCHEMBL238285 | 0.77 | TSHR (0.40) | ALDH1A1MAPTTHRBELANEKMT2A | |
| SCHEMBL2578321 | 0.77 | ALDH1A1 (0.41) | ALDH1A1MAPTTHRBELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745406-B2 | Curable composition | CEMEDINE CO., LTD. (JP) | 2017-08-29 | — | — | US | disclosed |
| EP-2412756-B1 | CURABLE COMPOSITION | CEMEDINE CO LTD (JP) | 2016-12-21 | — | — | EP | disclosed |
| EP-2412756-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-02-01 | — | — | EP | disclosed |
| US-20120004371-A1 | CURABLE COMPOSITION | CEMEDINE CO., LTD. (JP) | 2012-01-05 | — | — | US | disclosed |