SCHEMBL23843840

SCHEMBL23843840

CC(C)C(NC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(COC(N)=O)cc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FAP Q12884 5/20 0.48
▸ MAP1LC3B Q9GZQ8 2/20 0.40
▸ SIRT2 Q8IXJ6 8/20 0.39
▸ SIRT1 Q96EB6 7/20 0.39
▸ SIRT3 Q9NTG7 3/20 0.38
▸ NPY1R P25929 2/20 0.38
▸ NPY4R P50391 2/20 0.38
▸ NPY5R Q15761 2/20 0.38
▸ NPY2R P49146 1/20 0.38
▸ SIRT5 Q9NXA8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27249189 1.00 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL23420151 1.00 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL14978945 1.00 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL28365735 0.95 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL23485287 0.95 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL22678894 0.95 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL17722931 0.95 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL23420078 0.95 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL20733059 0.95 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3
SCHEMBL25094983 0.95 FAP (0.48) FAPMAP1LC3BSIRT2SIRT1SIRT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11213592-B2 Antibody-sting agonist conjugates and their use in immunotherapy IMMUNESENSOR THERAPEUTICS, INC. (US) 2022-01-04 — — US disclosed
US-20210290774-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY IMMUNESENSOR THERAPEUTICS, INC. (US) 2021-09-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11213592-B2 Antibody-sting agonist conjugates and their use in immunotherapy STING1, CGAS, MAVS FAP 2096/4885MAP1LC3B 2588/4885SIRT2 3945/4885
US-20210290774-A1 ANTIBODY-STING AGONIST CONJUGATES AND THEIR USE IN IMMUNOTHERAPY STING1, CGAS, MAVS FAP 2096/4885MAP1LC3B 2588/4885SIRT2 3945/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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