Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 5/20 | 0.48 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 8/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 7/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.38 |
| ▸ | NPY1R | P25929 | 2/20 | 0.38 |
| ▸ | NPY4R | P50391 | 2/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27249189 | 1.00 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL23420151 | 1.00 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL23843840 | 1.00 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL28365735 | 0.95 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL23485287 | 0.95 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL22678894 | 0.95 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL17722931 | 0.95 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL23420078 | 0.95 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL20733059 | 0.95 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 | |
| SCHEMBL25094983 | 0.95 | FAP (0.48) | FAPMAP1LC3BSIRT2SIRT1SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3760233-B1 | ONE-POT PREPARATION PROCESS FOR ANTIBODY DRUG CONJUGATE INTERMEDIATE | MABPLEX INT CO LTD (CN) | 2023-07-12 | — | — | EP | disclosed |
| EP-3099681-B1 | CYTOTOXIC TUBULYSIN COMPOUNDS AND CONJUGATES THEREOF | TUBE PHARMACEUTICALS GMBH (AT) | 2020-12-09 | — | — | EP | disclosed |
| US-20180147294-A1 | ANTIBODY-DRUG CONJUGATES, COMPOSITIONS AND METHODS OF USE | IGENICA BIOTHERAPEUTICS, INC. | 2018-05-31 | — | — | US | disclosed |
| EP-2780039-B1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER (US) | 2017-11-29 | — | — | EP | disclosed |
| US-9764040-B2 | Spliceostatin analogs and methods for their preparation | PFIZER INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-20170014523-A1 | SPLICEOSTATIN ANALOGS AND METHOS FOR THEIR PREPARATION | PFIZER (US) | 2017-01-19 | — | — | US | disclosed |
| EP-2927227-A1 | ANTIBODY-LINKER-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND ANTICANCER DRUG COMPOSITION CONTAINING SAME | Celltrion, Inc. (KR) | 2015-10-07 | — | — | EP | disclosed |
| WO-2014107024-A1 | ANTIBODY-LINKER-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND ANTICANCER DRUG COMPOSITION CONTAINING SAME | 셀트리온 (KR) | 2014-07-10 | — | — | WO | disclosed |
| WO-2014068443-A1 | SPLICEOSTATIN ANALOGS | PFIZER INC. (US) | 2014-05-08 | — | — | WO | disclosed |
| WO-2013072813-A2 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | PFIZER INC. (US) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180147294-A1 | ANTIBODY-DRUG CONJUGATES, COMPOSITIONS AND METHODS OF USE | SDCBP, CD81, DSTN | FAP 2598/4885MAP1LC3B 302/4885SIRT2 4565/4885 |
| US-20170014523-A1 | SPLICEOSTATIN ANALOGS AND METHOS FOR THEIR PREPARATION | SF3B5, SF3B1, SNRPA1 | FAP 3551/4885MAP1LC3B 1462/4885SIRT2 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.