Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.41 |
| ▸ | BTN3A1 | O00481 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27435986 | 1.00 | POLRMT (0.41) | POLRMTBTN3A1CYP3A4CYP2C9DOT1L | |
| SCHEMBL23844047 | 1.00 | POLRMT (0.41) | POLRMTBTN3A1CYP3A4CYP2C9DOT1L | |
| SCHEMBL23844076 | 0.94 | POLRMT (0.42) | POLRMTBTN3A1CYP3A4CYP2C9DOT1L | |
| SCHEMBL27436005 | 0.94 | POLRMT (0.41) | POLRMTBTN3A1CYP3A4CYP2C9DOT1L | |
| SCHEMBL23843977 | 0.93 | POLRMT (0.41) | POLRMTBTN3A1CYP3A4CYP2C9DOT1L | |
| SCHEMBL27437016 | 0.93 | POLRMT (0.41) | POLRMTBTN3A1CYP3A4CYP2C9DOT1L | |
| SCHEMBL23844122 | 0.93 | POLRMT (0.41) | POLRMTBTN3A1CYP3A4CYP2C9DOT1L | |
| SCHEMBL23844123 | 0.93 | POLRMT (0.41) | POLRMTBTN3A1CYP3A4CYP2C9DOT1L | |
| SCHEMBL23844104 | 0.92 | POLRMT (0.42) | POLRMTBTN3A1CYP3A4CYP2C9 | |
| SCHEMBL27436579 | 0.92 | POLRMT (0.42) | POLRMTBTN3A1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030903-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030903-B2 | Antiviral compounds | GILEAD SCIENCES, INC. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20210292348-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030903-B2 | Antiviral compounds | EIF2AK2, MAVS, DUT | POLRMT 76/4885BTN3A1 4438/4885CYP3A4 1416/4885 |
| US-20210292348-A1 | ANTIVIRAL COMPOUNDS | EIF2AK2, MAVS, DUT | POLRMT 76/4885BTN3A1 4438/4885CYP3A4 1416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.