Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | PAK4 | O96013 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | GRK5 | P34947 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.37 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL92380 | 0.74 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1ATMNPC1NFKB1 | |
| SCHEMBL18811851 | 0.74 | ALDH1A1 (0.46) | ALDH1A1KDRCYP3A4KDM4E | |
| SCHEMBL244970 | 0.73 | KDR (0.56) | L3MBTL1KDRACVR1DYRK1AEPHB4 | |
| SCHEMBL28816219 | 0.73 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1ATMNPC1NFKB1 | |
| SCHEMBL27684583 | 0.73 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1ATMNPC1NFKB1 | |
| SCHEMBL3753666 | 0.73 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1ATMNPC1NFKB1 | |
| SCHEMBL26785663 | 0.72 | L3MBTL1 (0.65) | L3MBTL1ALDH1A1KDREPHB4CYP3A4 | |
| SCHEMBL515503 | 0.71 | GAA (0.59) | L3MBTL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20774126 | 0.71 | KDR (0.55) | L3MBTL1KDRACVR1DYRK1AEPHB4 | |
| Ammonia Solution, Strong SCHEMBL18398465 | 0.71 | KDR (0.55) | L3MBTL1KDRACVR1DYRK1AEPHB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188938-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | AKEBIA THERAPEUTICS, INC. (US) | 2021-09-23 | — | — | WO | disclosed |