Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 11/20 | 0.47 |
| ▸ | CES1 | P23141 | 10/20 | 0.47 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24488706 | 0.86 | CES2 (0.42) | CES2CES1AKT1MAPTALDH1A1 | |
| SCHEMBL18413421 | 0.78 | AKT1 (0.52) | CES2CES1AKT1MAPTALDH1A1 | |
| SCHEMBL18413409 | 0.76 | AKT1 (0.54) | CES2CES1AKT1MAPTALDH1A1 | |
| SCHEMBL19420680 | 0.76 | AKT1 (0.46) | CES2CES1AKT1MAPTALDH1A1 | |
| SCHEMBL21572126 | 0.75 | AKT1 (0.48) | CES2CES1AKT1MAPTALDH1A1 | |
| SCHEMBL25552738 | 0.71 | ALDH1A1 (0.42) | CES2CES1AKT1MAPTALDH1A1 | |
| SCHEMBL22924919 | 0.70 | AKT1 (0.47) | CES2CES1AKT1MAPTALDH1A1 | |
| SCHEMBL3258198 | 0.69 | AKT1 (0.50) | CES2CES1AKT1MAPTALDH1A1 | |
| SCHEMBL22109788 | 0.69 | ATM (0.40) | CES2CES1MAPTALDH1A1LMNA | |
| SCHEMBL20457465 | 0.69 | CES2 (0.47) | CES2CES1AKT1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021188978-A1 | PHOTOREACTIVE AND CLEAVABLE PROBES FOR TAGGING BIOMOLECULES | ACADEMIA SINICA (TW) | 2021-09-23 | — | — | WO | disclosed |