Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 10/20 | 0.47 |
| ▸ | CES1 | P23141 | 10/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14632252 | 0.83 | CES2 (0.45) | CES2CES1MAPTALDH1A1EGFR | |
| SCHEMBL19221755 | 0.82 | CES2 (0.52) | CES2CES1MAPTALDH1A1EGFR | |
| SCHEMBL20793843 | 0.80 | CES2 (0.45) | CES2CES1MAPTALDH1A1EGFR | |
| SCHEMBL16748125 | 0.80 | CES2 (0.45) | CES2CES1MAPTALDH1A1EGFR | |
| SCHEMBL27719292 | 0.78 | CES2 (0.50) | CES2CES1MAPTALDH1A1EGFR | |
| SCHEMBL22379873 | 0.78 | ALDH1A1 (0.44) | CES2CES1MAPTALDH1A1AKT1 | |
| SCHEMBL21282687 | 0.78 | TGM2 (0.42) | MAPTALDH1A1LMNASMN1; SMN2POLB | |
| SCHEMBL18869529 | 0.78 | CES2 (0.42) | CES2CES1MAPTALDH1A1EGFR | |
| SCHEMBL30924817 | 0.77 | ATM (0.37) | CES2CES1MAPTALDH1A1AKT1 | |
| SCHEMBL3431437 | 0.76 | GRIK1 (0.32) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10040893-B2 | Polymeric photoinitiators and photoinitiator monomers | COLOPLAST A/S (DK) | 2018-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10040893-B2 | Polymeric photoinitiators and photoinitiator monomers | ACMSD, AAAS, PPOX | CES2 1721/4885CES1 2461/4885MAPT 91/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.