Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPI | P34949 | 6/20 | 0.47 |
| ▸ | PHOSPHO1 | Q8TCT1 | 5/20 | 0.47 |
| ▸ | G6PD | P11413 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PMM2 | O15305 | 3/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 3/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21687118 | 0.87 | CRBN (0.52) | MPIPHOSPHO1G6PDALDH1A1TDP1 | |
| SCHEMBL21687130 | 0.82 | CASP3 (0.44) | MPIPHOSPHO1G6PDKDM4EALDH1A1 | |
| SCHEMBL21687127 | 0.81 | MPI (0.60) | MPIPHOSPHO1G6PDPMM2IDO1 | |
| SCHEMBL21687116 | 0.77 | CRBN (0.52) | MPIPHOSPHO1G6PDALDH1A1APOBEC3G | |
| SCHEMBL21687134 | 0.74 | MIF (0.42) | LMNAMAPTIDO1DDB1CRBN | |
| SCHEMBL21687125 | 0.73 | MPI (0.48) | MPIPHOSPHO1G6PDKDM4EALDH1A1 | |
| SCHEMBL21687119 | 0.72 | CRBN (0.48) | ALDH1A1TDP1DDB1CRBN | |
| SCHEMBL21687108 | 0.70 | CRBN (0.56) | ALDH1A1TDP1DDB1CRBN | |
| SCHEMBL21687132 | 0.68 | DDB1 (0.41) | ALDH1A1LMNATDP1IDO1DDB1 | |
| SCHEMBL25026488 | 0.67 | CRBN (0.80) | ALDH1A1TDP1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210292315-A1 | SELENIUM-CONTAINING ISOXAZOLAMINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | SHANGHAI XINGYE PHARMACEUTICAL TECHNOLOGY CO., LTD (CN) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210292315-A1 | SELENIUM-CONTAINING ISOXAZOLAMINE COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF | AIFM2, GPX1, AIFM1 | MPI 3496/4885PHOSPHO1 3147/4885G6PD 2053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.