SCHEMBL238481

SCHEMBL238481

COC(=O)N[C@H](C(=O)O)[C@@H](C)OC(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PYGL P06737 13/20 0.38
CYP2C9 P11712 1/20 0.38
KEAP1 Q14145 2/20 0.38
CTSS P25774 2/20 0.36
CTSK P43235 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21527698 1.00 PYGL (0.38) PYGLCYP2C9KEAP1CTSSCTSK
SCHEMBL2395128 0.87 CTSK (0.49) PYGLCYP2C9CTSSCTSK
SCHEMBL2418915 0.87 CTSK (0.49) PYGLCYP2C9CTSSCTSK
SCHEMBL8222608 0.87 CTSK (0.49) PYGLCYP2C9CTSSCTSK
SCHEMBL14453090 0.87 CTSK (0.49) PYGLCYP2C9CTSSCTSK
SCHEMBL14038647 0.87 CTSK (0.49) PYGLCYP2C9CTSSCTSK
SCHEMBL14039301 0.87 CTSK (0.49) PYGLCYP2C9CTSSCTSK
SCHEMBL6476152 0.87 CTSK (0.49) PYGLCYP2C9CTSSCTSK
SCHEMBL6640994 0.87 CTSK (0.49) PYGLCYP2C9CTSSCTSK
SCHEMBL12943346 0.85 CTSK (0.33) KEAP1CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121537485-A Cyclohexapeptide and preparation method and application thereof 未来多肽生物科技(烟台)有限公司 2026-02-17 CN disclosed
CN-120248044-A Cyclohexapeptide and preparation method and application thereof 陕西未来多肽生物科技有限公司 2025-07-04 CN disclosed
CN-119591674-A Cyclohexapeptide and preparation method and application thereof 陕西未来多肽生物科技有限公司 2025-03-11 CN disclosed
US-20230285378-A1 Anti-Viral Compounds ABBVIE INC. (US) 2023-09-14 US disclosed
US-10800789-B2 Antiviral compounds GILEAD PHARMASSET LLC (US) 2020-10-13 US disclosed
US-10800789-B2 Antiviral compounds GILEAD PHARMASSET LLC (US) 2020-10-13 US disclosed
EP-3699176-A2 ANTIVIRAL COMPOUNDS Gilead Pharmasset LLC (US) 2020-08-26 EP disclosed
US-20200123132-A1 ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC 2020-04-23 US disclosed
US-20190337960-A1 ANTIVIRAL COMPOUNDS GILEAD SCIENCES, INC. 2019-11-07 US disclosed
EP-3239153-B1 9-(1H-IMIDAZOL-5-YL)-1,11-DIHYDROISOCHROMENO[4',3':6,7]NAPHTHO[1,2-D]IMIDAZOLE DERIVATIVES AND THEIR USE AS INHIBITORS OF HCV NS5A GILEAD PHARMASSET LLC (US) 2019-05-08 EP disclosed
US-20140316144-A1 ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC 2014-10-23 US disclosed
EP-2692346-A1 An antiviral 1-phenyl-2,5-dibenzimidazol-5-yl-pyrrolidine derivative Abbvie Inc. (US) 2014-02-05 EP disclosed
EP-2692726-A1 Anti-viral compounds Abbvie Inc. (US) 2014-02-05 EP disclosed
US-20140018313-A1 ANTIVIRAL COMPOUNDS Gelead Sciences, Inc. 2014-01-16 US disclosed
US-20140018313-A1 ANTIVIRAL COMPOUNDS Gelead Sciences, Inc. 2014-01-16 US disclosed
WO-2013173488-A1 ANTIVIRAL COMPOUNDS INHIBITORS OF HCV NS5B GILEAD SCIENCES, INC. (US) 2013-11-21 WO disclosed
US-20130309196-A1 ANTIVIRAL COMPOUNDS GILEAD PHARMASSET LLC 2013-11-21 US disclosed
US-20120220562-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-08-30 US disclosed
US-20120004196-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2012-01-05 US disclosed
US-20110207699-A1 Anti-Viral Compounds Abbott Labaoratories (US) 2011-08-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140018313-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, ZC3HAV1 PYGL 2026/4885CYP2C9 3296/4885KEAP1 2326/4885
US-20230285378-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS PYGL 88/4885CYP2C9 3780/4885KEAP1 206/4885
US-20130309196-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SARS1 PYGL 844/4885CYP2C9 3743/4885KEAP1 3086/4885
US-20120220562-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS PYGL 88/4885CYP2C9 3780/4885KEAP1 206/4885
US-20110207699-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS PYGL 88/4885CYP2C9 3780/4885KEAP1 206/4885
US-20200123132-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, ZC3HAV1 PYGL 2026/4885CYP2C9 3296/4885KEAP1 2326/4885
US-10800789-B2 Antiviral compounds MAVS, EIF2AK2, SARS1 PYGL 844/4885CYP2C9 3743/4885KEAP1 3086/4885
US-20140316144-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SARS1 PYGL 844/4885CYP2C9 3743/4885KEAP1 3086/4885
US-20120004196-A1 Anti-Viral Compounds HAVCR2, EIF2AK2, MAVS PYGL 88/4885CYP2C9 3780/4885KEAP1 206/4885
US-20190337960-A1 ANTIVIRAL COMPOUNDS MAVS, EIF2AK2, SARS1 PYGL 844/4885CYP2C9 3743/4885KEAP1 3086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.