Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 6/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26513262 | 0.89 | JAK3 (0.42) | JAK3 | |
| SCHEMBL23569910 | 0.89 | JAK3 (0.42) | JAK3 | |
| SCHEMBL20314875 | 0.89 | JAK3 (0.34) | JAK3 | |
| SCHEMBL23569909 | 0.89 | JAK3 (0.42) | JAK3 | |
| SCHEMBL23308474 | 0.84 | KRAS (0.38) | — | |
| SCHEMBL23569903 | 0.84 | KRAS (0.38) | — | |
| SCHEMBL23569912 | 0.84 | KRAS (0.38) | — | |
| SCHEMBL23569701 | 0.81 | JAK3 (0.39) | JAK3HRH3 | |
| SCHEMBL22185432 | 0.81 | JAK3 (0.39) | JAK3HRH3 | |
| SCHEMBL20314877 | 0.81 | JAK3 (0.39) | JAK3HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230011726-A1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO LTD (CN) | 2023-01-12 | — | — | US | disclosed |
| US-20210292331-A1 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD (CN) | 2021-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230011726-A1 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | JAK3 2361/4885FAAH 3263/4885HRH3 4083/4885 |
| US-20210292331-A1 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | JAK3 2361/4885FAAH 3263/4885HRH3 4083/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.