Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 19/20 | 0.42 |
| ▸ | TXK | P42681 | 8/20 | 0.33 |
| ▸ | BTK | Q06187 | 7/20 | 0.33 |
| ▸ | ITK | Q08881 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23569910 | 1.00 | JAK3 (0.42) | JAK3TXKBTKITKPOLB | |
| SCHEMBL23569909 | 1.00 | JAK3 (0.42) | JAK3TXKBTKITKPOLB | |
| SCHEMBL23848396 | 0.89 | JAK3 (0.34) | JAK3 | |
| SCHEMBL20314875 | 0.88 | JAK3 (0.34) | JAK3POLB | |
| SCHEMBL23308474 | 0.83 | KRAS (0.38) | — | |
| SCHEMBL23569912 | 0.83 | KRAS (0.38) | — | |
| SCHEMBL23569903 | 0.83 | KRAS (0.38) | — | |
| SCHEMBL25120492 | 0.81 | MEN1 (0.33) | POLB | |
| SCHEMBL25039738 | 0.81 | MEN1 (0.33) | POLB | |
| SCHEMBL23569701 | 0.80 | JAK3 (0.39) | JAK3TXKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11787811-B2 | KRAS mutant protein inhibitors | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2023-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787811-B2 | KRAS mutant protein inhibitors | KRAS, NRAS, APC | JAK3 2361/4885TXK 2616/4885BTK 1261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.