Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | TPMT | P51580 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3337646 | 0.83 | MAPK1 (0.58) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL1381241 | 0.82 | MEN1 (0.64) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL7621025 | 0.81 | CES2 (0.59) | RAB9AGAAMEN1KMT2A | |
| SCHEMBL28094523 | 0.79 | CYP1A2 (0.68) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL30368186 | 0.78 | MAOA (0.44) | RAB9AMEN1KMT2AMAPT | |
| SCHEMBL156299 | 0.78 | HTT (0.73) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL660929 | 0.78 | LMNA (0.55) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL29599043 | 0.78 | LMNA (0.55) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL30307554 | 0.78 | HTT (0.73) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR | |
| SCHEMBL23850348 | 0.77 | CYP1A2 (0.44) | CYP1A2CYP3A4CYP2C19CYP2C9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883925-A1 | CYCLIC UREAS | Sironax Ltd (KY) | 2021-09-29 | — | — | EP | disclosed |