SCHEMBL6941899

SCHEMBL6941899

Cc1c(O)c(N(c2ccccc2)c2ccccc2)cc(O)c1N(c1ccccc1)c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.35
LMNA P02545 1/20 0.35
ESR1 P03372 1/20 0.33
TTR P02766 1/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
HKDC1 Q2TB90 1/20 0.31
ALDH1A1 P00352 4/20 0.31
TSHR P16473 2/20 0.31
FAAH O00519 1/20 0.31
PHGDH O43175 1/20 0.31
MGLL Q99685 1/20 0.31
GLA P06280 1/20 0.31
CYP2D6 P10635 2/20 0.31
KDM4E B2RXH2 2/20 0.31
CYP3A4 P08684 2/20 0.31
MAPT P10636 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8582938 0.76 POLB (0.37) LMNAESR1TTRHKDC1ALDH1A1
SCHEMBL2385266 0.73 POLB (0.39) HTTLMNAESR1TTRALOX5
SCHEMBL11409317 0.70 ALDH1A1 (0.44) HTTLMNAALDH1A1TSHRFAAH
SCHEMBL13826026 0.70 ALDH1A1 (0.44) HTTLMNAALDH1A1TSHRFAAH
SCHEMBL21626191 0.70 PTGS1 (0.48) HTTLMNAESR1TTRALOX5
SCHEMBL16067292 0.69 TRPA1 (0.45) HTTLMNAESR1PTGS1ALDH1A1
SCHEMBL18872978 0.69 ALDH1A1 (0.39) HTTLMNAESR1ALDH1A1TSHR
SCHEMBL12018935 0.68 ALDH1A1 (0.42) HTTLMNAALDH1A1TSHRFAAH
SCHEMBL8516743 0.68 ALDH1A1 (0.41) HTTLMNAHKDC1ALDH1A1TSHR
SCHEMBL12618603 0.67 MAPT (0.38) HTTESR1ALDH1A1TSHRFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1164178-B1 Electroluminescent devices having arylamine polymers EASTMAN KODAK CO (US) 2003-09-03 EP disclosed
EP-1164178-A1 Electroluminescent devices having arylamine polymers EASTMAN KODAK COMPANY (US) 2001-12-19 EP disclosed
US-6329086-B1 GOOD SOLUBILITY, EFFICIENCY AND STABILITY; EMITTING COLOR OF THE POLYMER CAN BE EASILY TUNED BY THE INCORPORATION OF DESIRED AROMATIC GROUP; POLYARYLENEVINYLENE EASTMAN KODAK COMPANY 2001-12-11 US disclosed