Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 2/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850452 | 0.83 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL23853450 | 0.82 | GAA (0.48) | SMN1; SMN2ALDH1A1DPP4DPP7KMT2A | |
| SCHEMBL16825158 | 0.81 | ALDH1A1 (0.46) | SMN1; SMN2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL23853735 | 0.80 | NPC1 (0.45) | SMN1; SMN2PPARGPPARAALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL29995401 | 0.80 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL23854114 | 0.75 | NPC1 (0.41) | SMN1; SMN2ALDH1A1MGLLDPP4DPP7 | |
| Trifluoroacetic Acid SCHEMBL23853076 | 0.75 | KMT2A (0.42) | PPARGPPARAALDH1A1MGLLKMT2A | |
| Trifluoroacetic Acid SCHEMBL23853666 | 0.74 | CXCL8 (0.41) | PPARGPPARAALDH1A1GRM5DPP4 | |
| Trifluoroacetic Acid SCHEMBL21590609 | 0.70 | SLC6A2 (0.49) | PPARGPPARAMGLLABHD6 | |
| SCHEMBL23519098 | 0.70 | PPARG (0.45) | PPARGPPARAALDH1A1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883925-A1 | CYCLIC UREAS | Sironax Ltd (KY) | 2021-09-29 | — | — | EP | disclosed |