Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL23853076

Clc1ccc(ON2CCC2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.42
PPARA Q07869 3/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 2/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
CYP2D6 P10635 1/20 0.42
CYP2C19 P33261 1/20 0.42
LIPE Q05469 2/20 0.41
HPGD P15428 2/20 0.40
RAB9A P51151 2/20 0.40
POLB P06746 1/20 0.40
HRH3 Q9Y5N1 7/20 0.38
PPARG P37231 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
FABP2 P12104 1/20 0.38
SLC22A12 Q96S37 1/20 0.38
MGLL Q99685 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL23853450 0.86 GAA (0.48) KMT2AMAPTRAB9AHRH3ALDH1A1
Trifluoroacetic Acid SCHEMBL23853735 0.78 NPC1 (0.45) KMT2APPARAMAPTMEN1HPGD
SCHEMBL4750348 0.77 HRH3 (0.46) KMT2AMAPTMEN1LIPEHPGD
Trifluoroacetic Acid SCHEMBL23852712 0.76 MEN1 (0.43) KMT2AMEN1HPGDRAB9APOLB
Trifluoroacetic Acid SCHEMBL23852876 0.75 SMN1; SMN2 (0.42) KMT2APPARACYP3A4PPARGALDH1A1
Trifluoroacetic Acid SCHEMBL23854114 0.73 NPC1 (0.41) KMT2AMAPTMEN1CYP1A2CYP3A4
Trifluoroacetic Acid SCHEMBL23853666 0.71 CXCL8 (0.41) KMT2APPARAMEN1CYP1A2CYP3A4
SCHEMBL9706430 0.71 LTA4H (0.45) KMT2AMEN1LIPEHPGDHRH3
Parachlorophenol SCHEMBL27659204 0.68 MAPK1 (0.56) KMT2APPARAMAPTMEN1CYP1A2
SCHEMBL27843363 0.68 ATM (0.42) KMT2AMAPTMEN1HPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3883925-A1 CYCLIC UREAS Sironax Ltd (KY) 2021-09-29 EP disclosed