SCHEMBL23853738

SCHEMBL23853738

O=c1cc(C(F)(F)F)nc(SCc2nnn[nH]2)[nH]1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ FABP4 P15090 5/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ KMT2A Q03164 2/20 0.54
▸ FABP3 P05413 1/20 0.54
▸ RAB9A P51151 1/20 0.44
▸ SCN9A Q15858 3/20 0.43
▸ HPGD P15428 2/20 0.38
▸ LMNA P02545 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ TSHR P16473 1/20 0.36
▸ CASP7 P55210 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24087940 0.78 MEN1 (0.55) FABP4MEN1KMT2AFABP3RAB9A
SCHEMBL23852226 0.78 MEN1 (0.53) FABP4MEN1KMT2AFABP3RAB9A
SCHEMBL31053414 0.78 MEN1 (0.53) FABP4MEN1KMT2AFABP3RAB9A
SCHEMBL20339427 0.75 SCN9A (0.36) MEN1KMT2ASCN9ALMNA
SCHEMBL26847224 0.75 FABP4 (0.60) FABP4MEN1KMT2AFABP3RAB9A
SCHEMBL24087901 0.74 DAO (0.43) FABP4MEN1KMT2AFABP3SCN9A
SCHEMBL24087886 0.74 DAO (0.43) MEN1KMT2ASCN9AHPGDLMNA
SCHEMBL24087925 0.74 FABP4 (0.60) FABP4MEN1KMT2AHPGD
SCHEMBL26847259 0.72 FABP4 (0.57) FABP4MEN1KMT2AFABP3SCN9A
SCHEMBL23849819 0.72 FABP4 (0.60) FABP4MEN1KMT2AFABP3RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024240882-A1 HETEROARYL AND HETEROCYCLIC COMPOUNDS FOR USE IN TREATING ACUTE INFLAMMATION TES PHARMA S.R.L. (IT) 2024-11-28 — — WO disclosed
CN-118496217-A Inhibitors of alpha-amino-beta-carboxyhexadienoic acid semialdehyde decarboxylase TES制药有限责任公司 2024-08-16 — — CN disclosed
US-20230381177-A1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE TES PHARMA S.R.L. (IT) 2023-11-30 — — US disclosed
US-20230381177-A1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE TES PHARMA S.R.L. (IT) 2023-11-30 — — US disclosed
US-20210379069-A1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE TES PHARMA S R L (IT) 2021-12-09 — — US disclosed
EP-3883930-A1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE Tes Pharma S.r.l. (IT) 2021-09-29 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230381177-A1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE ACMSD, GLS, ALDH7A1 FABP4 3410/4885MEN1 2572/4885KMT2A 1353/4885
US-20210379069-A1 INHIBITORS OF ALPHA-AMINO-BETA-CARBOXYMUCONIC ACID SEMIALDEHYDE DECARBOXYLASE ACMSD, GLS, ALDH7A1 FABP4 3410/4885MEN1 2572/4885KMT2A 1353/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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