Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 20/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6517491 | 1.00 | PTGIR (0.44) | PTGIRPTGDRPTGER1PTGER4PTGER3 | |
| SCHEMBL6517494 | 1.00 | PTGIR (0.44) | PTGIRPTGDRPTGER1PTGER4PTGER3 | |
| Acetic Acid SCHEMBL2479619 | 0.83 | SLC1A3 (0.35) | — | |
| SCHEMBL937100 | 0.83 | — | — | |
| SCHEMBL7705221 | 0.81 | USP2 (0.42) | — | |
| SCHEMBL14414058 | 0.81 | USP2 (0.42) | — | |
| SCHEMBL1062380 | 0.81 | — | — | |
| SCHEMBL2376563 | 0.80 | GPR119 (0.32) | — | |
| SCHEMBL2376559 | 0.80 | GPR119 (0.32) | — | |
| SCHEMBL25217734 | 0.79 | PLG (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3884934-A1 | MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO | Arena Pharmaceuticals, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |