Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27504693 | 0.78 | ALDH1A1 (0.54) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL31668450 | 0.78 | ALDH1A1 (0.54) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL23854171 | 0.77 | POLB (0.44) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL16009974 | 0.75 | POLB (0.48) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL28208533 | 0.75 | POLB (0.48) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL1075595 | 0.75 | POLB (0.48) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL30344008 | 0.72 | POLB (0.64) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL1180653 | 0.72 | POLB (0.64) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL996292 | 0.72 | ABCB1 (0.50) | POLBMAPTLMNAHTTALDH1A1 | |
| SCHEMBL27732409 | 0.71 | ALDH1A1 (0.64) | POLBMAPTLMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3883605-A1 | METHODS OF TREATING CANCER | Ariagen, Inc. (US) | 2021-09-29 | — | — | EP | disclosed |