Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23871932 | 0.79 | GPR119 (0.53) | — | |
| SCHEMBL25216966 | 0.77 | — | — | |
| SCHEMBL19211581 | 0.75 | CHRNB2 (0.32) | — | |
| SCHEMBL19211588 | 0.75 | CHRNB2 (0.32) | — | |
| SCHEMBL19211575 | 0.75 | CHRNB2 (0.32) | — | |
| SCHEMBL10242155 | 0.73 | MAPT (0.34) | — | |
| SCHEMBL25233923 | 0.72 | DAO (0.34) | — | |
| SCHEMBL1936310 | 0.70 | HSD11B1 (0.37) | — | |
| SCHEMBL17112985 | 0.68 | SMYD3 (0.30) | — | |
| SCHEMBL19212832 | 0.68 | SMYD3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4126855-B1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | HOFFMANN LA ROCHE (CH) | 2024-04-24 | — | — | EP | disclosed |
| EP-4126855-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. Hoffmann-La Roche AG (CH) | 2023-02-08 | — | — | EP | disclosed |
| WO-2021190727-A1 | COMPOUNDS AND THEIR USE IN THE TREATMENT OF BACTERIAL INFECTION | F. HOFFMANN-LA ROCHE AG (CH) | 2021-09-30 | — | — | WO | disclosed |