Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.54 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.54 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.54 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.54 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.54 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.54 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.54 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.54 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.54 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.54 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.54 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.54 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.54 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.54 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.54 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.54 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.54 |
| ▸ | PSMA8 | Q8TAA3 | 1/20 | 0.54 |
| ▸ | PSMB7 | Q99436 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2385815 | 1.00 | MGLL (0.54) | MGLLPSMB11PSMA7PSMB1PSMA1 | |
| SCHEMBL29111127 | 0.92 | DGKA (0.64) | DGKAALDH1A1TRPV1ESR1ADRA2A | |
| SCHEMBL29111126 | 0.92 | DGKA (0.64) | DGKAALDH1A1TRPV1ESR1ADRA2A | |
| SCHEMBL16681273 | 0.92 | DGKA (0.64) | DGKAALDH1A1TRPV1ESR1ADRA2A | |
| SCHEMBL30516315 | 0.92 | DGKA (0.64) | DGKAALDH1A1TRPV1ESR1ADRA2A | |
| SCHEMBL15015438 | 0.92 | DGKA (0.64) | DGKAALDH1A1TRPV1ESR1ADRA2A | |
| SCHEMBL9547798 | 0.91 | DGKA (0.61) | DGKAALDH1A1MAPTTRPV1ESR1 | |
| SCHEMBL2387062 | 0.89 | CNR1 (0.55) | MGLLDGKACNR1ALDH1A1MAPT | |
| SCHEMBL2387072 | 0.89 | CNR1 (0.55) | MGLLDGKACNR1ALDH1A1MAPT | |
| SCHEMBL28380918 | 0.88 | EPHX2 (0.59) | MGLLDGKACNR1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465939-B2 | Aging-related circulating particle-associated lipoprotein B oxidase (apoBNOX) and inhibitors thereof | NOX TECHNOLOGIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20110217401-A1 | Aging-Related Circulating Particle-Associated Lipoprotein B Oxidase (apoBNOX) and Inhibitors Thereof | NOX TECHNOLOGIES, INC. | 2011-09-08 | — | — | US | disclosed |