Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 4/20 | 0.55 |
| ▸ | MGLL | Q99685 | 1/20 | 0.53 |
| ▸ | DGKA | P23743 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.50 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387062 | 1.00 | CNR1 (0.55) | CNR1MGLLDGKAALDH1A1MAPT | |
| SCHEMBL2386450 | 0.92 | DGKA (0.62) | DGKAALDH1A1S1PR4S1PR1S1PR3 | |
| SCHEMBL2387070 | 0.91 | CNR1 (0.54) | CNR1MGLLDGKAALDH1A1MAPT | |
| SCHEMBL2385815 | 0.89 | MGLL (0.54) | CNR1MGLLDGKAALDH1A1MAPT | |
| SCHEMBL2385809 | 0.89 | MGLL (0.54) | CNR1MGLLDGKAALDH1A1MAPT | |
| SCHEMBL21753482 | 0.87 | EPHX2 (0.59) | CNR1MGLLDGKAALDH1A1MAPT | |
| SCHEMBL2383925 | 0.86 | TRPV1 (0.51) | CNR1MGLLDGKAALDH1A1MAPT | |
| SCHEMBL2383933 | 0.86 | TRPV1 (0.51) | CNR1MGLLDGKAALDH1A1MAPT | |
| SCHEMBL1316201 | 0.85 | MGLL (0.56) | CNR1MGLLDGKAALDH1A1MAPT | |
| SCHEMBL1316198 | 0.85 | MGLL (0.56) | CNR1MGLLDGKAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8465939-B2 | Aging-related circulating particle-associated lipoprotein B oxidase (apoBNOX) and inhibitors thereof | NOX TECHNOLOGIES, INC. (US) | 2013-06-18 | — | — | US | disclosed |
| US-20110217401-A1 | Aging-Related Circulating Particle-Associated Lipoprotein B Oxidase (apoBNOX) and Inhibitors Thereof | NOX TECHNOLOGIES, INC. | 2011-09-08 | — | — | US | disclosed |