Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.32 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.31 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19653130 | 0.98 | KDM4E (0.41) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL19769479 | 0.93 | KDM4E (0.41) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL23862327 | 0.93 | L3MBTL1 (0.44) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL23862253 | 0.93 | L3MBTL1 (0.44) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL17760817 | 0.93 | KDM4E (0.37) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL19653241 | 0.93 | KDM4E (0.37) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL23862331 | 0.93 | KDM4E (0.37) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL19653190 | 0.92 | L3MBTL1 (0.41) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL23862342 | 0.91 | KDM4E (0.43) | KDM4EATML3MBTL1TDP1PTGER4 | |
| SCHEMBL23862285 | 0.91 | KDM4E (0.43) | KDM4EATML3MBTL1TDP1PTGER4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11130747-B2 | Plurality of host materials and an organic electroluminescence device comprising the same | ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) | 2021-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11130747-B2 | Plurality of host materials and an organic electroluminescence device comprising the same | SOD1, TERT, TELO2 | KDM4E 2736/4885ATM 3138/4885L3MBTL1 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.