Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.47 |
| ▸ | THRA | P10827 | 9/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18932863 | 0.93 | TSHR (0.42) | THRBTHRAGAA | |
| SCHEMBL18998857 | 0.91 | THRA (0.47) | THRBTHRAGAAALDH1A1 | |
| SCHEMBL6656537 | 0.88 | THRA (0.53) | THRBTHRAGAA | |
| SCHEMBL18932864 | 0.87 | ABL1 (0.43) | THRBTHRA | |
| SCHEMBL18998874 | 0.86 | THRA (0.41) | THRBTHRAALDH1A1 | |
| SCHEMBL18932862 | 0.85 | CTSB (0.42) | THRBTHRAGAAALDH1A1 | |
| SCHEMBL18932874 | 0.84 | RAB9A (0.44) | THRBTHRAALDH1A1 | |
| SCHEMBL6657849 | 0.84 | THRA (0.47) | THRBTHRAGAA | |
| SCHEMBL6659271 | 0.82 | THRA (0.43) | THRBTHRAGAAALDH1A1 | |
| SCHEMBL18932871 | 0.81 | EPHX1 (0.39) | THRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3181556-B1 | MICROMOLECULE COMPOUND, METHOD OF SYNTHESIS AND APPLICATION THEREOF | TECHNODERMA MEDICINES PTE LTD (CN) | 2021-09-29 | — | — | EP | disclosed |