Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRC | Q99895 | 1/20 | 0.49 |
| ▸ | EIF4A1 | P60842 | 2/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
| ▸ | RARB | P10826 | 3/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | BRS3 | P32247 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864747 | 0.90 | CTRC (0.45) | CTRCEIF4A1AKR1C2AKR1C1LTB4R2 | |
| SCHEMBL13454810 | 0.86 | CTRC (0.55) | CTRCEIF4A1AKR1C2AKR1C1LTB4R2 | |
| SCHEMBL23864186 | 0.81 | TSHR (0.52) | CTRCAKR1C2AKR1C1LTB4R2RARB | |
| SCHEMBL13454812 | 0.79 | CTRC (0.48) | CTRCEIF4A1AKR1C2AKR1C1LTB4R2 | |
| SCHEMBL17540353 | 0.78 | CTRC (0.49) | CTRCEIF4A1AKR1C2AKR1C1LTB4R2 | |
| SCHEMBL23864206 | 0.78 | POLB (0.46) | THRATHRBCA1CA2 | |
| SCHEMBL14681833 | 0.77 | CTRC (0.48) | CTRCEIF4A1AKR1C2AKR1C1RARB | |
| SCHEMBL17540354 | 0.76 | CTRC (0.45) | CTRCEIF4A1AKR1C2AKR1C1LTB4R2 | |
| SCHEMBL14681834 | 0.75 | CTRC (0.50) | CTRCEIF4A1AKR1C2AKR1C1LTB4R2 | |
| SCHEMBL13454809 | 0.74 | XDH (0.48) | CTRCEIF4A1AKR1C2AKR1C1LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |