Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 3/20 | 0.31 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864599 | 0.92 | HTT (0.36) | BCHELMNA | |
| SCHEMBL23864239 | 0.88 | — | — | |
| SCHEMBL23864210 | 0.87 | HPGD (0.35) | AVPR2LMNA | |
| SCHEMBL23864539 | 0.86 | HPGD (0.33) | BCHEAVPR2LMNAMAPK1NLRP1 | |
| SCHEMBL23864447 | 0.82 | AKR1C3 (0.36) | LMNA | |
| SCHEMBL23864573 | 0.81 | — | — | |
| SCHEMBL23864738 | 0.81 | HPGD (0.34) | LMNA | |
| SCHEMBL23864267 | 0.74 | TAS1R3 (0.41) | LMNA | |
| SCHEMBL23864683 | 0.73 | NR1H4 (0.35) | MAPK1 | |
| SCHEMBL11511287 | 0.73 | HSD17B1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |