Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864392 | 0.83 | HTT (0.30) | ALDH1A1HPGDKDM4EL3MBTL1LMNA | |
| SCHEMBL23864482 | 0.75 | TSHR (0.36) | ALDH1A1TSHRKMT2AMEN1CYP1A2 | |
| SCHEMBL23864326 | 0.75 | LMNA (0.43) | ALDH1A1MAPTPPARGNPC1RAB9A | |
| SCHEMBL23864264 | 0.72 | PARP1 (0.32) | — | |
| SCHEMBL23864637 | 0.71 | TXNRD1 (0.37) | ALDH1A1RAB9AKMT2AMEN1CYP1A2 | |
| SCHEMBL23864366 | 0.71 | MAPT (0.37) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL23864723 | 0.71 | MAPT (0.37) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL23864539 | 0.70 | HPGD (0.33) | ALDH1A1MAPTHPGDKDM4ELMNA | |
| SCHEMBL23864239 | 0.70 | — | — | |
| SCHEMBL23864246 | 0.70 | TXNRD1 (0.36) | ALDH1A1MAPTRAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |