Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | UBE2M | P61081 | 1/20 | 0.37 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864691 | 0.89 | ALDH1A1 (0.47) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL16127859 | 0.77 | ALDH1A1 (0.54) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL13102688 | 0.74 | KCNMA1 (0.60) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL4293229 | 0.74 | KDM4E (0.48) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL13334328 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL16088604 | 0.73 | KDM4E (0.48) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL1015519 | 0.71 | MEN1 (0.47) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL4193660 | 0.71 | GAA (0.54) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL6177644 | 0.70 | KDM4E (0.57) | ALDH1A1KDM4EMAPTHPGDGAA | |
| SCHEMBL11880437 | 0.70 | ALDH1A1 (0.40) | ALDH1A1KDM4EMAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |