Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864523 | 0.89 | ALDH1A1 (0.43) | ALDH1A1GAAMAPTLMNATDP1 | |
| SCHEMBL16127859 | 0.88 | ALDH1A1 (0.54) | ALDH1A1GAAMAPTLMNATDP1 | |
| SCHEMBL4293229 | 0.78 | KDM4E (0.48) | ALDH1A1GAAMAPTLMNAKDM4E | |
| SCHEMBL13102688 | 0.78 | KCNMA1 (0.60) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL16088604 | 0.76 | KDM4E (0.48) | ALDH1A1GAAMAPTLMNAKDM4E | |
| SCHEMBL23864601 | 0.76 | TRPM4 (0.51) | ALDH1A1GAAMAPTKDM4EHTT | |
| SCHEMBL1015519 | 0.75 | MEN1 (0.47) | ALDH1A1GAAMAPTKDM4EHPGD | |
| SCHEMBL6177644 | 0.74 | KDM4E (0.57) | ALDH1A1GAAMAPTLMNAKDM4E | |
| SCHEMBL10401308 | 0.73 | SMN1; SMN2 (0.57) | ALDH1A1KDM4EHSD17B10GRIK1 | |
| SCHEMBL16088610 | 0.72 | KMT2A (0.55) | ALDH1A1GAAMAPTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |