Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16088682 | 0.80 | APEX1 (0.74) | HPGDKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL16088712 | 0.71 | KDM4E (0.77) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL18181886 | 0.70 | KDM4E (0.70) | HPGDKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL13932577 | 0.69 | KDM4E (0.65) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL23864209 | 0.69 | PTGER4 (0.51) | ALDH1A1KMT2ALMNANR1H4MEN1 | |
| SCHEMBL16088749 | 0.69 | APEX1 (0.69) | HPGDALDH1A1HSD17B10KMT2AGAA | |
| SCHEMBL16088690 | 0.69 | APEX1 (0.79) | HPGDKDM4EALDH1A1KMT2AGAA | |
| SCHEMBL16127952 | 0.68 | ALDH1A1 (0.77) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL3580203 | 0.68 | MAPK14 (0.60) | HPGDKDM4EALDH1A1HSD17B10KMT2A | |
| SCHEMBL1034235 | 0.66 | HPGD (0.72) | HPGDKDM4EALDH1A1HSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |