Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.51 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864722 | 0.86 | ALDH1A1 (0.40) | PTGER4PTGER2LMNAKMT2APYGL | |
| SCHEMBL16088644 | 0.82 | KMT2A (0.60) | PTGER4PTGER2LMNAKMT2ACYP1A2 | |
| SCHEMBL16127850 | 0.80 | PTGER4 (0.67) | PTGER4PTGER2KMT2ACYP1A2CYP2C19 | |
| SCHEMBL23864280 | 0.80 | PYGL (0.53) | PTGER4PTGER2LMNAKMT2ACYP1A2 | |
| SCHEMBL16088672 | 0.79 | PTGER4 (0.63) | PTGER4PTGER2LMNAKMT2ACYP1A2 | |
| SCHEMBL16127851 | 0.77 | PTGER4 (0.67) | PTGER4PTGER2KMT2ACYP1A2CYP2C19 | |
| SCHEMBL16088682 | 0.74 | APEX1 (0.74) | LMNAKMT2ACYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL19799450 | 0.74 | PTGER4 (0.54) | PTGER4PTGER2LMNAKMT2ACYP1A2 | |
| SCHEMBL24735202 | 0.72 | PTGER4 (0.61) | PTGER4PTGER2LMNAKMT2ACYP1A2 | |
| SCHEMBL31518952 | 0.72 | PTGER4 (0.61) | PTGER4PTGER2LMNAKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |