Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864305 | 0.91 | NPC1 (0.47) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23864295 | 0.84 | POLB (0.46) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL16088634 | 0.78 | TRPV1 (0.52) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL16088655 | 0.78 | TRPV1 (0.52) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23864512 | 0.77 | ITGB1 (0.52) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23864237 | 0.76 | POLB (0.45) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23864215 | 0.75 | POLB (0.44) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23864567 | 0.75 | POLB (0.50) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23864709 | 0.72 | TSHR (0.36) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL23864538 | 0.72 | TSHR (0.41) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |