Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864567 | 0.90 | POLB (0.50) | POLBCA12CA1CA2CA9 | |
| SCHEMBL23864564 | 0.84 | NPC1 (0.50) | POLBRAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL23864512 | 0.80 | ITGB1 (0.52) | POLBRAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL23864237 | 0.79 | POLB (0.45) | POLBRAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL23864305 | 0.77 | NPC1 (0.47) | POLBRAB9ANPC1HPGDSMN1; SMN2 | |
| SCHEMBL16088671 | 0.75 | TRPV1 (0.56) | POLBRAB9ANPC1SMN1; SMN2TRPV1 | |
| SCHEMBL23864524 | 0.74 | FFAR1 (0.44) | RAB9ANPC1HPGDSMN1; SMN2TRPV1 | |
| SCHEMBL23864623 | 0.72 | ALDH1A1 (0.49) | POLBCA12CA1CA2CA9 | |
| SCHEMBL23864449 | 0.72 | ALDH1A1 (0.49) | POLBCA12CA1CA2CA9 | |
| SCHEMBL23864206 | 0.72 | POLB (0.46) | POLBCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |