Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 2/20 | 0.42 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23864305 | 0.83 | NPC1 (0.47) | POLBALDH1A1KMT2ANPC1RAB9A | |
| SCHEMBL23864648 | 0.81 | SMN1; SMN2 (0.40) | POLBALDH1A1KMT2AMAPTPLK1 | |
| SCHEMBL23864295 | 0.79 | POLB (0.46) | POLBALDH1A1KMT2AGAAMAPT | |
| SCHEMBL23864449 | 0.77 | ALDH1A1 (0.49) | POLBALDH1A1KMT2AGAAMAPT | |
| SCHEMBL23864623 | 0.77 | ALDH1A1 (0.49) | POLBALDH1A1KMT2AGAAMAPT | |
| SCHEMBL23864564 | 0.76 | NPC1 (0.50) | POLBALDH1A1KMT2AGAAMAPT | |
| SCHEMBL16088641 | 0.76 | PLK1 (0.56) | POLBALDH1A1GAAPLK1PLK3 | |
| SCHEMBL16088692 | 0.76 | PLK1 (0.58) | POLBALDH1A1KMT2AGAAMAPT | |
| SCHEMBL23864310 | 0.76 | PLK1 (0.43) | ALDH1A1KMT2AMAPTPLK1PLK3 | |
| SCHEMBL23864567 | 0.75 | POLB (0.50) | POLBALDH1A1KMT2AGAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968330-B1 | COMPOUNDS AND METHODS FOR INDUCING CHONDROGENESIS | SCRIPPS RESEARCH INST (US) | 2021-09-29 | — | — | EP | disclosed |