Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.49 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10147276 | 0.93 | USP2 (0.54) | HRH3MCOLN3USP2SMN1; SMN2L3MBTL1 | |
| SCHEMBL24240417 | 0.87 | L3MBTL1 (0.45) | HRH3MCOLN3L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL277165 | 0.82 | ALDH1A1 (0.54) | HRH3USP2SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL18118174 | 0.82 | HPGD (0.52) | HRH3USP2SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL847809 | 0.80 | ALDH1A1 (0.57) | USP2SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL18118180 | 0.80 | ALDH1A1 (0.57) | USP2SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL20004338 | 0.79 | HRH3 (0.50) | HRH3MCOLN3USP2SMN1; SMN2L3MBTL1 | |
| SCHEMBL15187981 | 0.79 | HRH3 (0.50) | HRH3MCOLN3SMN1; SMN2L3MBTL1ALDH1A1 | |
| SCHEMBL20251137 | 0.78 | MAPT (0.51) | HRH3SMN1; SMN2L3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10118804 | 0.77 | HRH3 (0.49) | HRH3MCOLN3USP2SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3689871-B1 | 4,6,7-TRISUBSTITUTED 1,2-DIHYDROPYRROL[3,4-C]PYRIDIN/PYRIMIDIN-3-ONE DERIVATIVE AND USE | SHANGHAI HAIYAN PHARMACEUTICAL TECH CO LTD (CN) | 2021-09-29 | — | — | EP | disclosed |