Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23865974 | 0.87 | HRH3 (0.49) | L3MBTL1KDM4EHTTMAPTKMT2A | |
| SCHEMBL6712387 | 0.83 | KDM4E (0.54) | L3MBTL1KDM4EHTTMAPTKMT2A | |
| SCHEMBL20841082 | 0.82 | RORC (0.46) | KDM4EMAPTALDH1A1HPGDHRH3 | |
| SCHEMBL17660607 | 0.82 | RORC (0.46) | KDM4EMAPTALDH1A1HPGDHRH3 | |
| SCHEMBL26326846 | 0.81 | MAPT (0.49) | KDM4EHTTMAPTKMT2AMEN1 | |
| SCHEMBL26326854 | 0.81 | MAPT (0.49) | KDM4EHTTMAPTKMT2AMEN1 | |
| SCHEMBL19937463 | 0.80 | DPP4 (0.38) | KDM4EHTTMAPTKMT2AMEN1 | |
| SCHEMBL31145170 | 0.79 | KDM4E (0.57) | KDM4EHTTMAPTKMT2AMEN1 | |
| SCHEMBL15383528 | 0.79 | KDM4E (0.57) | KDM4EHTTMAPTKMT2AMEN1 | |
| SCHEMBL939817 | 0.79 | KDM4E (0.49) | L3MBTL1KDM4EHTTMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3949969-A2 | BENZAZEPINE COMPOUNDS, CONJUGATES, AND USES THEREOF | Silverback Therapeutics, Inc. (US) | 2022-02-09 | — | — | EP | disclosed |