Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.47 |
| ▸ | CHRNG | P07510 | 1/20 | 0.47 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | CHRND | Q07001 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17410752 | 0.91 | PARP1 (0.53) | HPGDLMNAPARP1NPC1RAB9A | |
| Toluene SCHEMBL28293691 | 0.85 | CES2 (0.44) | HPGDLMNANPC1RAB9AHDAC4 | |
| SCHEMBL14700287 | 0.81 | PRSS1 (0.44) | LMNANPC1RAB9AHDAC4CHRNB4 | |
| SCHEMBL11988896 | 0.80 | ALDH1A1 (0.44) | HPGDLMNAPARP1HDAC8HDAC6 | |
| SCHEMBL28095639 | 0.79 | KDM4E (0.44) | HPGDLMNAHDAC4MEN1KMT2A | |
| Methyl Alcohol SCHEMBL28651962 | 0.79 | KDM4E (0.44) | HPGDLMNAHDAC4MEN1KMT2A | |
| SCHEMBL256587 | 0.79 | ALDH1A1 (0.45) | HPGDLMNANPC1RAB9ASLC6A2 | |
| SCHEMBL27279 | 0.78 | HDAC4 (0.46) | HPGDLMNAHDAC4MEN1KMT2A | |
| Benzene SCHEMBL29067363 | 0.78 | HDAC4 (0.46) | HPGDLMNAHDAC4MEN1KMT2A | |
| SCHEMBL6695613 | 0.78 | HDAC4 (0.46) | HPGDLMNAHDAC4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395793-B9 | PROCESS FOR THE PREPARATION OF ALPHA-FUNCTIONALIZED KETONES | IGM GROUP B V (NL) | 2021-09-29 | — | — | EP | disclosed |