SCHEMBL256587

SCHEMBL256587

Cc1ccc(C(=O)C2(O)CCCCC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.45
LMNA P02545 2/20 0.45
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
SMN1; SMN2 Q16637 4/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
HPGD P15428 3/20 0.42
NPC1 O15118 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2C19 P33261 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 1/20 0.41
PKM P14618 3/20 0.41
HTT P42858 2/20 0.41
ATM Q13315 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
NLRP1 Q9C000 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL28293691 0.87 CES2 (0.44) LMNACES2CES1SMN1; SMN2KMT2A
SCHEMBL3792897 0.85 FASN (0.34) ALDH1A1KMT2AMEN1HPGDKDM4E
SCHEMBL28505006 0.85 RAB9A (0.41) ALDH1A1LMNASMN1; SMN2KMT2AMEN1
SCHEMBL10943813 0.84 CES2 (0.39) CES2CES1
SCHEMBL6696391 0.84 SRD5A2 (0.39) ALDH1A1LMNASMN1; SMN2HPGDNPC1
SCHEMBL6692915 0.82 SRD5A2 (0.41) ALDH1A1LMNASMN1; SMN2KMT2AMEN1
SCHEMBL10943780 0.82 CES2 (0.41) CES2CES1
SCHEMBL28669997 0.81 CES2 (0.52) ALDH1A1CES2CES1SMN1; SMN2KMT2A
SCHEMBL3677117 0.81 FASN (0.36) ALDH1A1SMN1; SMN2KMT2AMEN1HPGD
SCHEMBL27416408 0.81 CES2 (0.45) ALDH1A1CES2CES1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109369406-B Photocatalytic synthesis method and application of 1-hydroxycyclohexyl phenyl ketone compound 甘肃金盾化工有限责任公司 2021-12-14 CN disclosed
US-10338436-B2 Method of manufacturing curved liquid crystal display device and curved liquid crystal display device SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-02 US disclosed
US-9790338-B2 Ion exchange membrane and method for manufacturing the same FUJIFILM CORPORATION (JP) 2017-10-17 US disclosed
US-9709852-B2 Curved liquid crystal display and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-9709852-B2 Curved liquid crystal display and method of manufacturing the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-07-18 US disclosed
US-20160362526-A1 ION EXCHANGE MEMBRANE AND METHOD FOR MANUFACTURING THE SAME FUJIFILM CORPORATION (JP) 2016-12-15 US disclosed
US-20160001238-A1 POLYMER FUNCTIONAL FILM AND METHOD FOR PRODUCING SAME FUJIFILM CORPORATION (JP) 2016-01-07 US disclosed
US-20150030839-A1 PRESSURE SENSITIVE ADHESIVE FOAMS AND ARTICLES THEREFROM 3M INNOVATIVE PROPERTIES COMPANY 2015-01-29 US disclosed
US-8536241-B2 (Meth)acryloyl pressure-sensitive foam adhesives 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-09-17 US disclosed
EP-1760102-B1 CATIONICALLY PHOTOPOLYMERIZABLE COMPOSITION AND OPTOELECTRONIC COMPONENT USING SAME THREE BOND CO LTD (JP) 2013-04-24 EP disclosed
US-8247569-B2 Cyclohexane derivative and pharmaceutical use thereof TORAY INDUSTRIES, INC. (JP) 2012-08-21 US disclosed
WO-2012028825-A1 ULTRA-THIN FILMS OF MOLECULARLY IMPRINTED POLYMERS CONFINED TO THE SURFACE OF A SUBSTRATE UNIVERSITE PARIS DIDEROT-PARIS 7 (FR) 2012-03-08 WO disclosed
US-20110201650-A1 CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 2011-08-18 US disclosed
EP-2065444-A1 PHOTOPOLYMERIZABLE COMPOSITION THREE BOND CO., LTD. (JP) 2009-06-03 EP disclosed
US-7455891-B2 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-11-25 US disclosed
US-7455891-B2 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORPORATION (US) 2008-11-25 US disclosed
EP-1451615-B1 METHOD FOR MODIFYING THE SURFACE OF BIOMEDICAL ARTICLES NOVARTIS AG (CH) 2007-11-14 EP disclosed
US-20070128441-A1 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORP. 2007-06-07 US disclosed
US-20070128441-A1 Process for the production of strongly adherent coatings CIBA SPECIALTY CHEMICALS CORP. 2007-06-07 US disclosed
EP-1760102-A1 CATIONICALLY PHOTOPOLYMERIZABLE COMPOSITION AND OPTOELECTRONIC COMPONENT USING SAME THREE BOND CO., LTD. (JP) 2007-03-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110201650-A1 CYCLOHEXANE DERIVATIVE AND PHARMACEUTICAL USE THEREOF CNR2, TRPV1, OPRL1 ALDH1A1 1195/4885LMNA 2744/4885CES2 88/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.