Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 11/20 | 0.47 |
| ▸ | HTR2A | P28223 | 7/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867474 | 0.83 | SRC (0.51) | SRCHTR2ADRD3HTR2C | |
| SCHEMBL23867532 | 0.73 | SRC (0.53) | SRCHTR2ADRD3HTR2C | |
| SCHEMBL23867517 | 0.71 | PDGFRA (0.36) | HTR2AHTR2CTRPV1 | |
| SCHEMBL23867486 | 0.70 | SRC (0.49) | SRCHTR2ADRD3HTR2C | |
| SCHEMBL23867478 | 0.70 | SRC (0.53) | SRCHTR2ADRD3HTR2C | |
| SCHEMBL27430034 | 0.69 | HTR2C (0.48) | HTR2AHTR2C | |
| SCHEMBL27430032 | 0.68 | HTR2C (0.60) | SRCHTR2AHTR2C | |
| SCHEMBL27429988 | 0.68 | HTR2C (0.61) | HTR2AHTR2C | |
| SCHEMBL27248309 | 0.67 | SRC (0.52) | SRCHTR2AHTR2C | |
| SCHEMBL23867515 | 0.66 | POLB (0.47) | SRCHTR2ADRD3HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195279-A2 | SMALL MOLECULE INHIBITORS OF ONCOGENIC CHD1L WITH PRECLINICAL ACTIVITY AGAINST COLORECTAL CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2021-09-30 | — | — | WO | disclosed |