Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2387016 | 1.00 | RAB9A (0.39) | RAB9ALMNANPC1HTTMAPT | |
| SCHEMBL30295460 | 0.82 | CYP2C19 (0.35) | RAB9ALMNANPC1HTTMAPT | |
| SCHEMBL13912716 | 0.78 | MAPT (0.35) | NPC1MAPTALDH1A1RORCCYP2C19 | |
| SCHEMBL2385539 | 0.76 | NPC1 (0.50) | RAB9ALMNANPC1HTTMAPT | |
| SCHEMBL2387203 | 0.73 | MEN1 (0.37) | LMNANPC1MAPTALDH1A1CYP2C19 | |
| SCHEMBL2387207 | 0.73 | MEN1 (0.37) | LMNANPC1MAPTALDH1A1CYP2C19 | |
| SCHEMBL5679288 | 0.69 | CA2 (0.55) | RAB9ALMNANPC1MAPTALDH1A1 | |
| SCHEMBL20730047 | 0.69 | RXRA (0.40) | MAPTALDH1A1MEN1POLBKMT2A | |
| SCHEMBL1928327 | 0.68 | STS (0.65) | RAB9ALMNANPC1MAPTALDH1A1 | |
| SCHEMBL2503247 | 0.68 | MAPT (0.41) | RAB9AMAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12048710-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-30 | — | — | US | disclosed |
| US-20220202837-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-06-30 | — | — | US | disclosed |
| US-11278554-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2022-03-22 | — | — | US | disclosed |
| US-20200046742-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-02-13 | — | — | US | disclosed |
| US-10434111-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-08 | — | — | US | disclosed |
| US-20160243135-A1 | Compositions and Methods for Modification of Biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-08-25 | — | — | US | disclosed |
| US-9260371-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-02-16 | — | — | US | disclosed |
| EP-1812031-B1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | UNIV CALIFORNIA (US) | 2015-06-24 | — | — | EP | disclosed |
| US-20130344527-A1 | Compositions and Methods for Modification of Biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-12-26 | — | — | US | disclosed |
| US-8461298-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-11 | — | — | US | disclosed |
| US-8431558-B2 | Compositions and methods for modification of biomolecules | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-04-30 | — | — | US | disclosed |
| US-20110213123-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-09-01 | — | — | US | disclosed |
| US-7807619-B2 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-10-05 | — | — | US | disclosed |
| US-20090068738-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-03-12 | — | — | US | disclosed |
| US-20060110782-A1 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12048710-B2 | Compositions and methods for modification of biomolecules | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-20220202837-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-20130344527-A1 | Compositions and Methods for Modification of Biomolecules | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-10434111-B2 | Compositions and methods for modification of biomolecules | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-20090068738-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-11278554-B2 | Compositions and methods for modification of biomolecules | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-20160243135-A1 | Compositions and Methods for Modification of Biomolecules | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-20110213123-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-20200046742-A1 | COMPOSITIONS AND METHODS FOR MODIFICATION OF BIOMOLECULES | PTMS, QPCT, ANPEP | RAB9A 4440/4885LMNA 1871/4885NPC1 4502/4885 |
| US-20060110782-A1 | cycloalkyne compounds reacting with an azide moiety on a target biomolecule, by biochemical conjugation; for its application in vivo (on the cell surface or intracellularly) or in vitro (synthesis of peptides); labeling | PTMS, QPCT, DNPEP | RAB9A 4140/4885LMNA 3610/4885NPC1 4228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.