SCHEMBL23870352

SCHEMBL23870352

CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC=O)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FCER2 P06734 4/20 0.58
MMP1 P03956 3/20 0.58
REN P00797 2/20 0.53
MME P08473 2/20 0.53
MMP2 P08253 2/20 0.53
MMP3 P08254 2/20 0.53
MMP7 P09237 1/20 0.51
ERAP2 Q6P179 1/20 0.50
ERAP1 Q9NZ08 1/20 0.50
LNPEP Q9UIQ6 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10272569 0.88 MMP1 (0.62) FCER2MMP1MMEMMP2MMP3
SCHEMBL2873585 0.87 MME (0.62) MMEMMP2MMP7
SCHEMBL7302253 0.86 FCER2 (0.61) FCER2MMP1RENMMEMMP2
SCHEMBL22300787 0.86 MEN1 (0.59) MMEMMP2MMP7
SCHEMBL23870381 0.86 FCER2 (0.61) FCER2MMP1RENMMEMMP2
SCHEMBL242142 0.85 FCER2 (0.60) FCER2MMP1RENMMEMMP2
SCHEMBL242141 0.85 FCER2 (0.60) FCER2MMP1RENMMEMMP2
SCHEMBL17132263 0.84 FCER2 (0.59) FCER2MMP1RENMMP2MMP3
SCHEMBL30573682 0.84 FCER2 (0.59) FCER2MMP1RENMMP2MMP3
SCHEMBL16023850 0.83 FCER2 (0.52) FCER2MMP1RENMMP2MMP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021195183-A1 COMPOSITIONS AND METHODS FOR INHIBITING PROTEIN EMBRYONIC ECTODERM DEVELOPMENT ACTIVITY AND TREATING DISEASE EXO THERAPEUTICS, INC. (US) 2021-09-30 WO disclosed