Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 4/20 | 0.36 |
| ▸ | CTSS | P25774 | 3/20 | 0.36 |
| ▸ | CTSL | P07711 | 4/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.31 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485391 | 0.80 | CNR2 (0.39) | CTSBCTSSCTSLCTSKCNR2 | |
| SCHEMBL3704763 | 0.79 | FFAR3 (0.39) | CNR2ALDH1A1CYP2C19CYP2C9MAPT | |
| SCHEMBL23870439 | 0.79 | ALDH1A1 (0.37) | CTSBCTSSCTSLALDH1A1CYP2C19 | |
| SCHEMBL1573844 | 0.77 | FFAR3 (0.40) | CNR2ALDH1A1CYP2C19MAPT | |
| SCHEMBL23870433 | 0.77 | ALDH1A1 (0.38) | CTSBCTSSALDH1A1SHMT1SHMT2 | |
| SCHEMBL1839678 | 0.75 | CTSK (0.52) | CTSBCTSSCTSLCTSKALDH1A1 | |
| SCHEMBL8683974 | 0.74 | CYP2C19 (0.36) | CTSBCTSSCTSLCNR2ALDH1A1 | |
| SCHEMBL14088075 | 0.74 | CYP1A2 (0.38) | CTSBCTSSCTSLCNR2ALDH1A1 | |
| SCHEMBL5112211 | 0.74 | CNR2 (0.36) | CTSBCTSSCTSLCNR2ALDH1A1 | |
| SCHEMBL5101551 | 0.74 | NPSR1 (0.43) | CTSBCTSSCTSLCNR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195183-A1 | COMPOSITIONS AND METHODS FOR INHIBITING PROTEIN EMBRYONIC ECTODERM DEVELOPMENT ACTIVITY AND TREATING DISEASE | EXO THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |