Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 4/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | DAO | P14920 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1187679 | 0.72 | IDO1 (0.57) | IDO1SORT1DHODHDAOALDH1A1 | |
| SCHEMBL10119694 | 0.72 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL19629953 | 0.71 | — | — | |
| SCHEMBL11110220 | 0.70 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL802733 | 0.67 | ALDH1A1 (0.40) | ALDH1A1POLB | |
| SCHEMBL29934381 | 0.65 | IDO1 (0.50) | IDO1SORT1DHODHDAOALDH1A1 | |
| SCHEMBL19315723 | 0.64 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL4016737 | 0.63 | ALDH1A1 (0.33) | SORT1DHODHDAOALDH1A1HTT | |
| SCHEMBL14878750 | 0.63 | IDO1 (0.47) | IDO1SORT1DHODHDAO | |
| SCHEMBL17149248 | 0.63 | IDO1 (0.56) | IDO1SORT1DHODHDAOALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021194954-A1 | SUBSTITUTED AZOLE DIONE COMPOUNDS WITH ANTIVIRAL ACTIVITY | STEMLINE THERAPEUTICS, INC. (US) | 2021-09-30 | — | — | WO | disclosed |