Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
| ▸ | SORT1 | Q99523 | 3/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23519914 | 0.78 | MGLL (0.33) | ALDH1A1NPSR1GSK3AGSK3BMGLL | |
| SCHEMBL4330983 | 0.73 | ACHE (0.46) | ALDH1A1TSHRHSD17B10MGLL | |
| SCHEMBL14314260 | 0.73 | MGLL (0.36) | ALDH1A1NPSR1GSK3AGSK3BMGLL | |
| SCHEMBL4005408 | 0.72 | ACHE (0.49) | ALDH1A1TSHRHSD17B10MGLL | |
| SCHEMBL24846324 | 0.67 | ALDH1A1 (0.38) | ALDH1A1POLBTSHRNPSR1HSD17B10 | |
| SCHEMBL20872300 | 0.67 | GSK3A (0.31) | ALDH1A1GSK3AGSK3BMGLL | |
| SCHEMBL14608278 | 0.65 | ALDH1A1 (0.38) | ALDH1A1GSK3AGSK3BMGLL | |
| SCHEMBL24285588 | 0.65 | GSK3A (0.30) | GSK3AGSK3BMGLL | |
| SCHEMBL9313710 | 0.65 | GRIA1 (0.42) | ALDH1A1POLBNPSR1HSD17B10L3MBTL1 | |
| SCHEMBL720415 | 0.64 | MAOA (0.46) | PDE3BPDE3AGSK3AGSK3BMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1708995-B1 | ASPARTATES USEFUL AS COMPONENTS IN COATING COMPOSITIONS AND THEIR PREPARATION | BAYER MATERIALSCIENCE LLC (US) | 2013-02-27 | — | — | EP | disclosed |
| EP-1666461-B1 | Polyaspartimides useful as reactive components for polyisocyanates in two-component polyurethane coating compositions | BAYER MATERIALSCIENCE AG (DE) | 2009-06-24 | — | — | EP | disclosed |
| US-7307140-B2 | Polyaspartimides | BAYER MATERIALSCIENCE LLC (US) | 2007-12-11 | — | — | US | disclosed |
| EP-1708995-A1 | ASPARTATES USEFUL AS COMPONENTS IN COATING COMPOSITIONS AND THEIR PREPARATION | Bayer MaterialScience LLC (US) | 2006-10-11 | — | — | EP | disclosed |
| EP-1666461-A2 | Polyaspartimides useful as reactive components for polyisocyanates in two-component polyurethane coating compositions | Bayer MaterialScience AG (DE) | 2006-06-07 | — | — | EP | disclosed |
| US-20060106194-A1 | Polyaspartimides | BAYER MATERIALSCIENCE LLC | 2006-05-18 | — | — | US | disclosed |
| WO-2005073188-A1 | ASPARTATES USEFUL AS COMPONENTS IN COATING COMPOSITIONS AND THEIR PREPARATION | BAYER MATERIALSCIENCE LLC (US) | 2005-08-11 | — | — | WO | disclosed |
| US-20050159560-A1 | PROCESS FOR PREPARING ASPARTATES | COVESTRO DEUTSCHLAND AG (DE) | 2005-07-21 | — | — | US | disclosed |
| US-6911501-B1 | Reacting a di- or polyamine with an unsaturated ester and then reacting the resultant product with a maleimide, useful as reactive component for polyisocyanates in two-component polyurethane coating formulation | BAYER MATERIALSCIENCE LLC (US) | 2005-06-28 | — | — | US | disclosed |