Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 5/20 | 0.33 |
| ▸ | GRM1 | Q13255 | 4/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29324232 | 0.78 | CYP17A1 (0.35) | CYP17A1CYP1A2HTR3APIK3CAMTOR | |
| SCHEMBL30098893 | 0.76 | HTR6 (0.42) | HTR3AMETAP2 | |
| SCHEMBL23858812 | 0.74 | HTR3A (0.44) | HTR3AMETAP2SLC40A1PIK3CAMTOR | |
| SCHEMBL23771391 | 0.73 | UTS2R (0.38) | GRM1SLC40A1 | |
| SCHEMBL23872096 | 0.72 | HTR3A (0.40) | HTR3AMETAP2PIK3CAMTOR | |
| SCHEMBL24229270 | 0.71 | SLC40A1 (0.36) | GRM1SLC40A1 | |
| SCHEMBL24376134 | 0.71 | SLC40A1 (0.36) | GRM1SLC40A1 | |
| Potassium Ion SCHEMBL23858590 | 0.70 | HTR3A (0.39) | CYP17A1CYP1A2HTR3APIK3CAMTOR | |
| SCHEMBL22133201 | 0.70 | SLC40A1 (0.38) | GRM1SLC40A1 | |
| SCHEMBL20971252 | 0.66 | HPRT1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021191359-A1 | MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2021-09-30 | — | — | WO | disclosed |