Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 12/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CYBB | P04839 | 2/20 | 0.45 |
| ▸ | NOX3 | Q9HBY0 | 2/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | BCHE | P06276 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437677 | 0.77 | KMT2A (0.50) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL23875509 | 0.77 | KMT2A (0.50) | MAPTGAAMEN1KMT2ATDP1 | |
| SCHEMBL25913327 | 0.74 | NOX1 (0.59) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL6482475 | 0.74 | NOX1 (0.51) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL6492859 | 0.74 | MAPT (0.52) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL6481927 | 0.74 | NOX1 (0.54) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL6490302 | 0.73 | NOX1 (0.47) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL6494144 | 0.72 | NOX1 (0.50) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL3645420 | 0.71 | NOX1 (0.40) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL6483338 | 0.71 | NOX1 (0.54) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2023-06-08 | — | — | US | disclosed |
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174485-A1 | LIPOXYGENASE INHIBITORS | ALOX15B, ALOX12, ALOX15 | NOX1 482/4885MAPT 1601/4885GAA 525/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.