Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.33 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30058049 | 0.83 | KDM4E (0.40) | CSNK2A2FGFR2KDRCSNK1A1CSNK1D | |
| SCHEMBL23875575 | 0.83 | KDM4E (0.40) | CSNK2A2FGFR2KDRCSNK1A1CSNK1D | |
| SCHEMBL25783488 | 0.70 | KDM4E (0.38) | CSNK2A2FGFR2KDRCSNK1A1CSNK1D | |
| SCHEMBL25798557 | 0.68 | CYP19A1 (0.43) | HTTSMN1; SMN2CYP19A1 | |
| SCHEMBL25792508 | 0.66 | EGLN3 (0.47) | HTTSMN1; SMN2CYP19A1CYP3A4 | |
| SCHEMBL25783415 | 0.66 | MMP2 (0.51) | HTTSMN1; SMN2CYP3A4CYP2D6KCNH2 | |
| SCHEMBL23875628 | 0.65 | ALDH1A1 (0.44) | HTTSMN1; SMN2 | |
| SCHEMBL22044246 | 0.65 | MAPT (0.59) | HTTSMN1; SMN2CYP3A4CYP2D6NQO2 | |
| SCHEMBL23875556 | 0.62 | SMN1; SMN2 (0.41) | GSK3BHTTSMN1; SMN2CYP19A1 | |
| SCHEMBL26729883 | 0.62 | IMPDH2 (0.53) | HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021195346-A1 | LIPOXYGENASE INHIBITORS | SRI INTERNATIONAL (US) | 2021-09-30 | — | — | WO | disclosed |